Microsoft should take a cue from the industrial economist, Clarence Edwin Ayres, who said
"A little inaccuracy saves a world of explanation."
Chubby Knowledge is meant to be a continuation of Fat Knowledge blog (http://fatknowledge.blogspot.com) looking at our planet's and country's most important scientific, technological, and hilarious issues.
What follows next is a fairly high-level summary of Dr Thornton's U of Oregon research on changing protein receptors. Basically, what he found was he could change forward "ancestral" proteins by altering a limited number of receptors. However, to change backward modern proteins, additional modifications needed to be made. He deduced that during evolution, in addition to specific changes to ancestral proteins that actually account their ability to do new things, there are also "silent" changes (that evolved by chance along with the significant changes) that don't actually affect the behavior of the modern ones. However, they do prevent the modern proteins from going back to the original function (unless they too are removed). Since the ancestral proteins can go forward with or without the silent changes, but the modern proteins only work in the ancestral form without the silent changes, reverse evolution is far less likely to occur.The Belgian biologist Louis Dollo was the first scientist to ponder reverse evolution. “An organism never returns to its former state,” he declared in 1905, a statement later dubbed Dollo’s law.
To see if he was right, biologists have reconstructed evolutionary history. In 2003, for example, a team of scientists studied wings on stick insects. They found that the insects’ common ancestor had wings, but some of its descendants lost them. Later, some of those flightless insects evolved wings again.
Yet this study did not necessarily refute Dollo’s law. The stick insects may indeed have evolved a new set of wings, but it is not clear whether this change appeared as reverse evolution at the molecular level. Did the insects go back to the exact original biochemistry for building wings, or find a new route, essentially evolving new proteins?
ordered him to cease selling the iPhone application. This charge rested on the claim that the MTA owns the copyright to the schedule data and that Schoenfeld’s use of the data violates that copyright.Unfortunately for the MTA, the charge
has no basis in legal reality. As the Supreme Court held in the seminal case Feist Publications v. Rural Telephone Service, 499 U.S. 340 (1991), pure facts are not copyrightable, and train schedules have long fallen under this rubric of pure fact. The MTA can claim a copyright on the presentation of its train schedules, but the train schedule information itself falls under Feist.I thought I had read (perhaps on Fat Knowledge?) about the Frankfurt train system (or some other German city) doing the same type of thing, but I can't find that story anywhere.
The average vehicle being traded in gets about 15.8 miles per gallon (6.33 gallons per hundred miles), and the average new vehicle that replaces it gets about 25.4 m.p.g. (3.94 gallons/100 miles).There is substantial fuel saving in this. As Fat Knowledge has pointed out (and Edward Glaeser agrees),
The jump from 10 to 20 m.p.g., for example, saves more gas than the one from 20 to 40 m.p.g. The move from 10 to 11 m.p.g. can save nearly as much as the leap from 33 to 50 m.p.g.Mr Glaeser goes on to say that this is better than high-speed rail because the savings start immediately. But it reinforces our car dependent way of life. And as the Wall Street Journal points out, it's really expensive.
In a nutshell, getting older cars off the road and substituting them with more fuel-efficient models appears to cost about $365 for each ton of carbon-dioxide emissions that are saved. ... The government estimates of the cost of carbon emissions ... are in the neighborhood of $28 a ton. So, Mr. Knittel asks, could the program ever actually be cost-effective, environmentally-speaking? Sure—if all the clunkers had stayed on the road, racking up mileage and emissions year after year for 60 years each, then it actually makes sense.Buying more fuel-efficient cars does "save money" for the drivers, but the bill only benefits people who can afford to drive. Since in general, people that drive to work are wealthier than those who take public transit, the Cash for Clunkers program, in general, does not help the people that need it most. One even greener rider for the bill that would help the less wealthy would be to allow the $4500 credit to be used for mass transit passes.
"They told me that I had to live up under the Julia Tuttle Causeway," says Barclay. "I said, 'How come I have to live under the Julia Tuttle Causeway?' They said, 'If you want to go home, this is where you got to go.' "Bill O'Reilly can rejoice that in Indiana, however, there's one less predator on the streets. One Mr Daniels was arrested during a "meet-up", thinking he was going to score big with three girls, only to find that all of them were undercover cops (who didn't know each other).Barclay has a driver's license issued to him at the time of his release. His address is listed as Julia Tuttle Causeway.
Like many of the sex offenders on supervised release, Barclay is required to be here between 6 p.m. and 7 a.m. During the day, many of the felons leave for jobs or to visit their families.
What is this? A center for ants? How can we be expected to teach children to learn how to read... if they can't even fit inside the building? |
The device is remarkable for the level of miniaturization and for the complexity of its parts, which is comparable to that of 18th century clocks. It has over 30 gears. When a date was entered via a crank (now lost), the mechanism calculated the position of the Sun, Moon, or other astronomical information such as the location of other planets. Since the purpose was to position astronomical bodies with respect to the celestial sphere, with reference to the observer's position on the surface of the earth, the device was based on the geocentric model.
The device was clearly a navigational instrument used in alien spaceships, which "tells us how little we know about the wisdom which the gods whispered into the ears of their darlings".